Successful Bone Marrow Transplant for Thalassemia: Mr. Arif, a 12-year-old boy from Dhaka, had been suffering from thalassemia since birth. His parents sought advanced treatment at Apollo Hospitals Chennai, where the medical team, led by Dr. Revathi Raj, performed a successful bone marrow transplant. The procedure was done using a matched sibling donor, and within months, Arif fully recovered. His case highlighted the hospital's expertise in treating complex blood disorders and its excellent infection control practices
Bone Marrow Transplant for Leukemia: Mrs. Samira, a 35-year-old mother from Chittagong, was diagnosed with acute myeloid leukemia. After multiple cycles of chemotherapy in Bangladesh, she was referred to Apollo Chennai for a bone marrow transplant. Dr. Sandeep and his team performed a successful allogeneic transplant, and Mrs. Samira achieved complete remission. The hospital's advanced treatment protocols and comprehensive follow-up care ensured her smooth recovery
Successful Transplant for Lymphoma: Mr. Habib, a 40-year-old from Dhaka, had a relapsed case of non-Hodgkin’s lymphoma. He was treated at Apollo Chennai with a stem cell transplant. The transplant was performed by a skilled team of oncologists and hematologists, and the procedure was a success, allowing him to return to Bangladesh cancer-free. Mr. Habib’s story showcases Apollo's cutting-edge technology and personalized care for Bangladeshi patients.
Bone marrow transplant is a recommended therapy for patients with certain types of cancers or diseases.
Bone marrow transplantation (BMT) is a life-saving medical procedure that involves the replacement of damaged or diseased bone marrow with healthy bone marrow stem cells.
Apollo Hospitals stands as one of the best hospitals for bone marrow transplant in India, offering advanced technologies and treatment procedures. With a highly qualified BMT team and stringent infection control norms, Apollo ensures the highest standards of care.
Apollo Hospitals, India, has performed over 1500 transplants with an excellent success rate, making it a trusted name in BMT for both domestic and international patients.
Bone marrow transplant is a medical procedure that replaces damaged or destroyed bone marrow with healthy bone marrow stem cells. It is used to treat diseases like leukemia, lymphoma, myeloma, and other genetic disorders.
Stem cells are parent cells found in the bone marrow that divide and mature into different types of blood cells, including white cells, platelets, and red blood cells. They are usually found inside the bone marrow spaces of large bones but can also travel through the blood system. A small percentage of white blood cells circulating in our veins are stem cells.
The transplant procedure does not involve surgery for the patient or donor and is considered very safe. Stem cells regenerate within a few days, and nothing is lost permanently in the body, unlike a kidney transplant. Stem cells are infused into the patient through a live blood transfusion.
Stem cell transplant is an exciting and well-established treatment for several cancers and blood diseases for the past few decades.
Who Can Be A Donor For An Allogeneic Transplant?
Matching is done by blood tests alone, and siblings are likely to provide the best match. Parents are not usually good matches. The donor must be in good health.
Collecting Bone Marrow
This is carried out under general anesthesia, involving the removal of marrow from the hip bones. The patient or donor stays overnight in the hospital to recover.
How Are The Stem Cells Collected?
Stem cell harvesting is done following daily injections of a growth factor, taking about 3 hours. The stem cells can even be frozen.
What Is Umbilical Cord Blood Transplantation?
Cord blood is rich in stem cells and can be used instead of bone marrow for transplantation. It is of high quality and very potent in producing blood cells.
The transplantation process consists of three main steps:
Peripheral stem cell harvest is done usually on the 4th / 5th / 6th day. The patient will be made to lie down on a couch and a drip will be put into the vein of each arm and the procedure takes about 3 hours.
Blood will be collected from one arm, via the drip, into a machine called a centrifuge, which spins it to separate out the peripheral stem cells.
These are collected and the remaining blood is returned through the drip in the other arm. The Peripheral stem cells can even be frozen until the patient has had the high-dose treatment.
About a week or two before the bone marrow harvest is done, the patient (or the donor, for an Allogeneic transplantation) may have 1 to 2 units of blood taken. This will be given back during the bone marrow harvest.
The harvest itself is carried out under general anesthesia, so one will feel nothing. It involves the removal of some marrow from inside the bones at the back and front of the pelvis. (The hip bones).
The patient or donor will have to stay in the hospital overnight to recover fully from the general anesthesia. Usually, it feels sore for a few days and mild painkillers may be required. These will be administered by the nurses or doctors before the patient leaves the hospital.
On occasions when the patient does not have a good matched relative / unrelated donor, a partially matched, unrelated cord blood with adequate cell dose would be an option.
This is the blood that is left behind in the placenta and the umbilical cord after the delivery of a baby. Cord blood is rich in peripheral stem cells and can be used instead of bone marrow for transplantation.
A day or more after the intensive chemotherapy is completed; the patient will start to feel slightly better. The patient’s own, or the donated bone marrow or peripheral stem cells or cord blood will then be given through the central line into a vein. They will find their way back via the bloodstream to the bones, where they will start to grow and develop into mature blood cells
It will be at least two or three weeks before some of the ‘new’ blood cells are released into the bloodstream, and it may be up to six weeks before one can leave the hospital.
Bone Marrow Transplant Fully Matched costs about 15 Lacs INR* and Half Matched about 30 Lacs INR*. These are approximate tentative pricing. The total cost of a bone marrow transplant varies based on the type of transplant, the patient’s condition, and other factors. For precise cost details, it is advisable to consult with us directly.
*conditions apply
Please note that the price quoted is indicative only and can vary upon actual and in person assessment. Any specialized investigations, management of any other illness, extended hospital stay, treatment prior surgery, stay in Chennai etc... would cost additional. The above cost does not include an outside stay.
Patients suffering from the following diseases may benefit from BMT