Dr A Srinivas Kumar

Educational Qualifications

• FACC (USA) at ACC, Chicago in 2008

• DM (Cardiology) at Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow in June 1998

• MD (Gen. Med.) at Osmania Medical College, Hyderabad in June 1994

• MBBS at Osmania Medical College, Hyderabad, in December 1989

Presently working as

• Senior Consultant, Cardiologist, Director Cardiology & Clinical Research, Apollo Hospitals, Jubilee Hills

• Professor of Medicine, Apollo ISMR, Hyderabad.

• Chairman, Facts Professional Services (FPS) & Founder, Director & CEO - FACTS – Fraternity of Advanced Cardiovascular Techniques & solutions - FPS- Largest CV professional group in India.

• Founding Course Director – Advance Cardio Vascular Solutions – India (ACVS – INDIA)/TCT INDIA, South Asia Conference - India’s Premier Interventional Experience

‍Earlier Experiences

• Professor, General Medicine, Prathima Institute of Medical Sciences, Karimnagar (2010- 2017)

• Assistant & Associate Professor, General Medicine Prathima Institute of Medical Sciences, Karimnagar (2001- 2010)

• Chairman, Cardio Vascular Sciences & Chief Cardiologist, Citizens Hospitals, Nallagandla, Hyderabad (2014-2018)

• ‍Chief of Medical Services, Citizens Hospitals (2016-2018)

• Senior Consultant Cardiologist, Director, Cardiac Catheterization Laboratory & Invasive Cardiology, Care Hospitals, Banjara Hills, Hyderabad (2000-2014)

• Director and Head Clinical Research Department, Care Group of Hospitals, India (2008-2014)

• Managing Director, Life Hospitals, Shivam Road, Hyderabad (2012-2014)

• Past - President, Andhra Pradesh Cardiology Society of India (APCSI)

• Executive Member, National CSI (2007-2009, 2013-2015)

• National Convenor, Cardiac Imaging, CSI (2010-2012)

• Chairman, CSI - National Interventional Council, India (2018-2019)

Awards and credentials

• State 2^nd Rank in Andhra Pradesh MBBS Entrance Examination.

• S.R. Rao Research Award for best thesis in MD General Medicine “A study of clinical profile of cases of Sickle cell disorder in adults”.

• Founder Editor of National Medical Journal “Post Graduate Medical Clinics of Osmania’’.

• Selected as a reviewer for International Journal “Catheterization & Cardiovascular Diagnosis’’ in 1998.

• President for 2009-10, Cardiological Society of India, AP Chapter.

• Executive Committee member, Cardiological Society of India 2007-09.

• Chairman, CSI- National Interventional Council 2017-19.

• Faculty for training Interventional Cardiologists from the USA for Transseptal puncture technique training – St Judes Co. Initiative to train Interventional & EP Cardiologists of the USA.

• Faculty for SING LIVE Course in Singapore, 2006-08.

• Faculty for CIT - China Interventional Therapeutics - 2009.

• Faculty for CCT-Kobe, Japan - 2009.

• Faculty for Angioplasty Summit, Seol, Korea-2010.

• Faculty for TCT, USA - 2011, 2012.

• Live Case Operator for Procedure Demonstration to TCT, USA 2012, 2019.

• Program Director & Founder of ACVS (Advance Cardio Vascular Solutions) India/TCT India, South Asia National Conference.

• Scientific advisor and Product concepts & device analyzer for Relysis India, S3V Vascular technologies, Medtronic & Boston Scientific, India.

‍Research

Research experience in multicenter trials

• ‍PRINCIPAL INVESTIGATOR for Nephric–II Study – A Randomized Comparison of Iapamiro vs. Iopamidal in Diabetic Renal Insufficiency patients-Sponsored by GE Health Care –Appreciated as Worlds' leading recruiter for enrolling a maximum no of patients.

• ‍PRINCIPAL INVESTIGATOR – COREL C Multicenter Stent Study-Paclitaxel eluting, Non-polymeric, Nonporous carbon-carbon coated Cobalt-chromium stent: Clinical and Angiographic Evaluation. Sponsored by Relysis India Pvt. Ltd. - 2^nd leading recruiter for the study.

• PRINCIPAL INVESTIGATOR- RE-DEEM STUDY – Randomized Dabigatran Etexilate dose-finding study in patients with Acute Coronary syndromes post index Event with additional risk factors for cardiovascular complications also receiving aspirin and clopidogrel: Multicenter, prospective placebo-controlled, group does escalation trial-Sponsored by Boehringer Ingelheim.- 2^nd leading recruiter in the world.

• CO-INVESTIGATOR - a multinational, multicenter, randomized, parallel-group, Double-blind study to assess the efficacy and safety of 1 mg, 5Mg, and 20 mg tid of oral sildenafil in the treatment of Subjects aged 18 years and over with pulmonary arterial Hypertension (PAH)- A Multicenter PAH study sponsored by Pfizer Int. Ltd.- Leading recruiters in the world.

• ‍PRINCIPAL INVESTIGATOR- SPIRIT WOMEN CLINICAL EVALUATION: A clinical evaluation of the Xience-V Everolimus eluting coronary stent system in the treatment of women with Denovo coronary artery lesion (single arm study protocol) – Leading recruiter in the world.

• PRINCIPAL INVESTIGATOR –Xience-V Everolimus eluting coronary stent system (EECSS) India - Post-marketing Registry-appreciated for faster enrollment rate per month.

• PRINCIPAL INVESTIGATOR – AMI- Stem cell study – A Randomized, double-blind Multicentric, Placebo-controlled, Single dose, Phase-II Study assessing the safety and efficacy of Intravenous ex vivo cultured adult allogenic mesenchymal stem cells in patients with STEMI.- Sponsored by STEMPEUTICS Research Ltd.

• CO-INVESTIGATOR. – A Randomized, double-blind multicentric, Placebo-controlled, Single dose, Phase-II Study assessing the safety and efficacy of Intramuscular ex vivo cultured adult allogenic mesenchymal stem cells in patients with critical limb Ischemia.- Sponsored by STEMPEUTICS Research Ltd.

• PRINCIPAL INVESTIGATOR- Prospective Evaluation of Advanced Glycosylation End-products in chronic heart failure patients - Type II DM with stable Heart failure patients (Phase II)

• CO-INVESTIGATOR - ART (Arterial Revascularization Trial) ART is a multi-center, international, randomized trial evaluating whether the use of both mammary arteries during coronary artery bypass grafting (CABG) improves survival and reduces the chance of recurrent chest pain and/or the need for further intervention (including surgery)compared to using one mammary artery. ART is supported by grants from the Medical Research Council and the British Heart Foundation.

• Evaluation of acute safety and efficacy of the Basal Annuloplasty Cardia Externally device in the treatment of Functional Mitral valve Regurgitation (Phase II) - Experienced in DP/DT, Experienced in Tissue Doppler Echocardiography.

• Multicenter Evaluation of Coronary Dual Source CT angiography in patients with Intermediate Risk of Coronary Artery Stenosis- Leading recruiters in the World.

• CEC MEMBER – BIOFLOW- INDIA.

Publications

• ‍ Immediate and follow-up results of Inoue balloon mitral valvotomy in juvenile rheumatic mitral stenosis. N. Sinha A. Kapoor, A. Sreenivas Kumar, M. Shahi, S. Radhakrishnan, S. Shrivastava, P.K. Goel. Journal of Heart Valve & Disease, 1997, 6:6.

• Influence of Sub valvular pathology on immediate results and follow-up events of Inoue balloon mitral valvotomy. A. Sreenivas Kumar, A. Kapoor, N. Sinha, S. Tewari, P.K. Goel, C.V. Umeshan, M. Shahi. Accepted for publication in Int. J. Cardiol.

• Smallaortic annulus: A Functional definition. Probal. K. Ghosh, Sanjeev Kumar, Shantanu Pandey, A. Sreenivas Kumar, N. Sinha, M. Shahi. Annals of Asian cardiovascular and thoracic surgery October 98.

• Small (<21mm) aortic valve prostheses - A clinical and hemodynamic evaluation. A. Sreenivas Kumar, Prabhat Kumar, M. Shahi, N. Sinha, Sanjeev Kumar, Shantanu Pandey, Probal K. Ghosh. Journal of Heart Valve Disease 98.

• Periodic Intermittent Electromechanical Dissociation: Hemodynamic Correlate of a Malfunctioning Mechanical Prostheses Letter to the Ed. P.K. Goel, M. Shahi, A. Sreenivas Kumar, R.K. Singh. Cath Cardiovasc Diagn. Nov. 97.

• Results of Inoue balloon mitral valvotomy in juvenile rheumatic mitral stenosis. Let. to Ed. A. Kapoor, A. Sreenivas Kumar. Int. J. Cardiol. 1998, 66: 97-98

• A study of clinical profile of cases of “Aplastic Anemia and their response to treatment with Cyclosporine-A’’. A. Sreenivas Kumar, Vijay Mohan, Raghuramulu M, Chandrakant P, Satyanarayana Ch, Venkateshwar Rao R. Post Graduate Medical Clinics of Osmania 1994, 1.1.

• Newer Antimicrobials Review article. A. Sreenivas Kumar, Vijay Mohan, Leelavati, Satyanarayana Ch, Sahay B.K, Prakasham A. Post Graduate Medical Clinics of Osmania 1994, 1.1.

• Post myocardial infarct patient. Review article. A. Sreenivas Kumar, Promod Kumar, A.K. Srivastava, P. Krishnam Raju. Postgraduate Medical Clinics of Osmania 1994, 1.2

• Respiratory failure and arterial blood gas analysis. Emergency Medicine review. A. Sreenivas Kumar, P. Vijay Mohan, Raghuramulu M, Chandrakant P, Satyanarayana Ch. Post Graduate Medical Clinics of Osmania 1994,1.2.

• Percutaneous closure of the ductus by controlled release coils. A. Sreenivas Kumar, Aditya Kapoor, N. Sinha, M. Shahi, P.K. Goel, S. Radhakrishnan, S. Shrivastava. Asian Annals of Cardiovascular and thoracic surgery.

• Angiographic sizing of the patent ductus arteriosus- Relevance in the coil era. A. Sreenivas Kumar, P.K. Goel, M. Shahi. Int Journal of Cardiol

• Inoue balloon mitral commissurotomy (IBMC) in patients with atrial septal aneurysm (ASA). A. Sreenivas Kumar, P.K. Goel, A. Kapoor, C.V. Umeshan, N. Sinha Int. Journal of Cardiol.

• Effect of Inoue Balloon mitral valvotomy in patients with severe PAH-Immediate and long-term results. C.V. Umeshan, A. Sreenivas Kumar, A. Kapoor, N. Sinha, P.K. Goel Journal Of Heart Valve & Disease, 1999.

• Inoue balloon mitral commissurotomy (IBMC) in patients with atrial septal aneurysm (ASA). PK Goel, A. Sreenivas Kumar, Kapoor, N. Garg, Int. Journal Of Cardiology 2001.

• Non-invasive evaluation of Coronary flow collaterals- An echo and Angio correlation-Anne Anjaneyulu, K. Raghu, A. Sreenivas Kumar, P. Krishnam Raju, P. Raghava Raju American Society of Echocardiography June 2008

• Nephrotoxicity of Iodixanol versus iopamidol in patients with chronic kidney disease and diabetes mellitus undergoing coronary angiographic procedures –Warren Lasky, Peter Aspelin, Charles Davidson, A. Sreenivas Kumar, etal. Am. Heart Journal 2009; 158.

• Retrograde Transcatheter Closure of Ventricular Septal Defects in Children Using The Amplatzer Duct Occluder II Nageswara Rao Koneti, MD, DM, Raghava Raju Penumatsa, MD, DM, Vasudevan Kanchi, MBBS, DCH, A. Sreenivas Kumar, MD, DM, Cath Cardiovasc. Interventions 2011.

• Renal Denervation – Dr. VenkatSram & Dr. A. Sreenivas Kumar, Journal of Hypertension 2014 (Nature Publication).

• Indigenous Stent Technologies - Examining Clinical Data – Review Article in Int. Cardiology 2015 (Future Medicine Publication).

• Pharmacy Invasive approach – A new paradigm in Acute MI Management – STEMI India text Book -2015.

• Renal Sympathetic Denervation – Current Status & Future Prospects – CSI Hypertension reviews 2020.

• Dual Antiplatelet therapy usage Beyond One year/One month: trials versus real-world Practice– CSI yearbook 2020.

• Takotsubo Cardiomyopathy– CSI year Book 2019.

• CSI- NIC Data 2018 – IHJ 18.07.2020.

• The report of Indian Coronary Intervention Data of 2017 - IHJ 04. 2019.

• Is Cardiology in India ready to shift from Solo to Group Practice – European HJ Feb 2019.

• Invasive Hemodynamic Assessment of Coronary Stenosis – Utility & Pitfalls – CSI year Book 2018.

• Cardiovascular Disease in India – A 360 Degree Overview –National Medical Journal of Armed Forces India 2019.

• Reversible LV Dysfunction after Transcatheter Aortic Valve Replacement (TAVR) – IJCC 2020.

Papers Published

• Study of Multi-Drug Resistant Salmonella infections. At A.P.I. Conference, Kakinada, 1991.

• A case report of Pseudomonas pyogenic meningitis - its complications and management. At A.P.I. Conference, Kakinada, 1991.

• A study of clinical profile of cases of “ Aplastic Anemia and their response to treatment with Cyclosporine-A’’. At A.P.I. Conference, Kurnool, 1994. (Award Session)

• A study of the clinical profile of cases of sickle cell disorder in adults. At A.P.I. Conference, Kurnool, 1994.

• A study of five cases of full-blown AIDS. At A.P.I. Conference, Kurnool, 1994. (Award Session).

• Scoring system to differentiate cirrhotic from non-cirrhotic portal hypertension.

• At A.P.I. Conference, Kurnool, 1994. Inoue balloon mitral valvotomy in patients with severe sub valvular pathology. At C.S.I. The conference, Bangalore,1996. Indian Heart Journal (abstract) Sept- Oct. 1996.

• Inoue balloon mitral valvotomy in juvenile rheumatic mitral stenosis. At C.S.I. The conference, Bangalore, 1996. Indian Heart Journal (abstract) Sept-Oct. 1996.

• Angiographic sizing of the patent ductus arteriosus (PDA) - relevance in the coil era. At C.S.I. The conference, Bangalore, 1996. Indian Heart Journal (abstract) Sept- Oct. 1996.

• Inoue balloon mitral valvotomy in mitral stenosis with severe pulmonary arterial hypertension. At C.S.I. The conference, Bangalore,1996. Indian Heart Journal (abstract) Sept-Oct. 1996.

• Inoue balloon mitral valvotomy in patients older than 40 years. At C.S.I. The conference, Bangalore,1996. Indian Heart Journal (abstract) Sept-Oct. 1996.

• Small(<21mm) aortic prostheses-A clinical and hemodynamic evaluation. At C.S.I. The conference, Calcutta,1997. Indian Heart Journal (abstract) Nov-Dec. 1997.

• Pretransplant coronary arteriography in diabetic patients with end-stage renal disease. At C.S.I. The conference, Calcutta,1997. Indian Heart Journal (abstract) Nov- Dec. 1997.

• Inoue balloon mitral commissurotomy (IBMC) - Predictors, Mechanisms and outcome of significant mitral regurgitation (MR). At C.S.I. The conference, Calcutta,1997. Indian Heart Journal (abstract) Nov-Dec. 1997.

• Inoue balloon mitral commissurotomy (IBMC) in patients with atrial septal aneurysm (ASA). At C.S.I. The conference, Calcutta, 1997. Indian Heart Journal (abstract) Nov-Dec. 1997.

• Decreasing subacute thrombosis-is it high-pressure post dilatation or something else? At C.S.I. The conference, Calcutta, 1997. Indian Heart Journal (abstract) Nov- Dec. 1997

• Balloon Mitral valvotomy in juvenile mitral stenosis: An Indian experience. S. Shrivastava, S. Radhakrishnan, A. Kapoor, N. Sinha, A. Sreenivas Kumar, P.K. Goel. Presented at the 2nd World Congress of Pediatric Cardiology and Cardiac Surgery, Honolulu, Hawaii, May 1997.

• Successful management of recurrent acute ischemic coronary events in Primary Antiphospholipid Syndrome. At International Symposium/C.M.E. on prevention of CAD. 11th Annual Conference of the Indian Society for Atherosclerosis Research, New Delhi, November 1998.

• Atherosclerotic CAD and angina in patients with congenital coronary anomalies. At International Symposium/C.M.E. on prevention of CAD. 11th Annual Conference of the Indian Society for Atherosclerosis Research, New Delhi, November 1998.

• Atherosclerotic CAD in patients with End Stage Renal Disease. At International Symposium/C.M.E. on prevention of CAD. 11th Annual Conference of the Indian Society for Atherosclerosis Research, New Delhi, November 1998.

• Inoue Balloon mitral valvotomy in patients < 12 years. At C.S.I. The conference, Bombay, 1998. Indian Heart Journal (abstract) Nov-Dec 1998.

• Analysis of etiology of moderate to severe MR in patients with < 12 years of age. At C.S.I. The conference, Bombay,1998. Indian Heart Journal (abstract) Nov-Dec 1998.

• Effect of oral Nicorandil on chronic MR and/or AR - A Clinical and Echocardiographic study. At C.S.I. The conference, Bombay, 1998. Indian Heart Journal (abstract) Nov-Dec 1998.

• Predictors, Mechanisms and Outcome of occurrence of MR post-Inoue balloon mitral valvotomy at World Heart Symposium, 1999, London.

• Coil Occasion of Coronary Cameral fistula-World Pediatric Cardiology Conference.